髓鞘（myelin sheath）是包裹在神經(jīng)細(xì)胞軸突外面的一層膜，即髓鞘由髓鞘細(xì)胞和細(xì)胞膜組成，是神經(jīng)細(xì)胞的質(zhì)膜沿著軸索的軸心螺旋纏繞形成的多層脂雙層結(jié)構(gòu)，髓鞘上有郎飛氏結(jié)，可使神經(jīng)沖動跳躍傳遞。髓鞘染色在病理診斷中有一定意義，髓鞘的病理變化分為早期、中期和晚期。在早期著色較深；病變中期階段的髓鞘變性形成脂滴，可用脂質(zhì)染色加以顯示，后期徹底潰變并被吞噬細(xì)胞清除，故不再有髓鞘的陽性結(jié)果。
      很多疾病都可以引起髓鞘的變化，Luxol Fast Blue髓鞘染色可以顯示病理情況下髓鞘是否完整、變性、壞死程度及修復(fù)情況，對神經(jīng)組織的病理診斷和研究均有意義，例如神經(jīng)纖維受損時(shí)，髓鞘可出現(xiàn)膨脹、曲折成球形、斷裂或脫鞘完全消失等改變。

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標(biāo)題:Small Extracellular Vesicles Derived from Altered Peptide Ligand-Loaded Dendritic Cell Act as A Therapeutic Vaccine for Spinal Cord Injury Through Eliciting CD4+ T cell-Mediated Neuroprotective Immunity

成員:Sikai Wang, Guanglei Li, Xiongjie Liang, Zexuan Wu, Chao Chen, Fawang Zhang, Jiawen Niu, Xuefeng Li, Jinglong Yan, Nanxiang Wang, Jing Li, Yufu Wang

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成員:Guo-Guo Chu, Jing Wang, Zhi-Bin Ding, Jin-Zhu Yin, Li-Juan Song, Qing Wang, Jian-Jun Huang, Bao-Guo Xiao, Cun-Gen Ma

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標(biāo)題:APART-QSM: An improved sub-voxel quantitative susceptibility mapping for susceptibility source separation using an iterative data fitting method

成員:Zhenghao Li, Ruimin Feng, Qiangqiang Liu, Jie Feng, Guoyan Lao, Ming Zhang, Jun Li, Yuyao Zhang, Hongjiang Wei

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標(biāo)題:Micro-nanofiber composite biomimetic conduits promote long-gap peripheral nerve regeneration in canine models

成員:Xianhao Dong, Yueyue Yang, Zheheng Bao, Adam C. Midgley, Feiyi Li, Shuxin Dai, Zhuangzhuang Yang, Jin Wang, Lihua Liu, Wenlei Li, Yayuan Zheng, Siyang Liu, Yang Liu, Weijian Yu, Jun Liu, Meng Fan, Meifeng Zhu, Zhongyang Shen, Gu Xiaosong, Deling Kong

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標(biāo)題:Hypoxic postconditioning drives protective microglial responses and ameliorates white matter injury after ischemic stroke

成員:Wei Zhang, Sijie Li, Ho Jun Yun, Wantong Yu, Wenjie Shi, Chen Gao, Jun Xu, Yu Yang, Linhui Qin, Yuchuan Ding, Kunlin Jin, Fengyong Liu, Xunming Ji, Changhong Ren

論文因子:5.5 發(fā)表期刊:CNS Neuroscience & Therapeutics pmid:37435771

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